Diagnostics for Statistical Variable Selection Methods for Prediction of Peptic Ulcer Disease in Helicobacter pylori Infection

Diagnostics for Statistical Variable Selection Methods for Prediction of Peptic Ulcer Disease in Helicobacter pylori Infection

BACKGROUND The development of accurate classification models depends upon the methods used to identify the most relevant variables. The aim of this article is to evaluate variable selection methods to identify important variables in predicting a binary response using nonlinear statistical models. Our goals in model selection include producing non-overfitting stable models that are interpretable...

[Helicobacter pylori infection in peptic ulcer disease].

Helicobacter pylori infection, chronic kidney disease, and peptic ulcer disease.

The recent publication of “Helicobacter pylori infection rate in chronic kidney disease and end-stage renal disease patients with peptic ulcer disease” is very interesting. Chang and Hu noted that “the H. pylori infection rate is lower in PUD patients with CKD and ESRD than in those without CKD.” There are many concerns regarding this report. First, the prevalence of peptic ulcer disease (PUD) ...

Helicobacter pylori infection in peptic ulcer disease and gastric malignancy.

Helicobacter pylori infection is the world's most common chronic infection in humans and is the cause of most gastritis cases. This infection is accepted as the etiology of the majority of peptic ulcers. It has been implicated as a significant contributing factor in the development of gastric malignancy--both gastric MALT lymphoma and gastric adenocarcinoma. Both endoscopic and non-endoscopic t...

Helicobacter pylori in peptic ulcer disease.

Since William Beaumont's classic description of gastric physiology in 1847, the focus of clinical practice and basic research concerning gastric and duodenal ulcers has centered on the secretion of acid and pepsin. In addition to these well-known factors (largely determined by heredity, age, and oral intake), the search for other agents that alter the mucosal barrier has identified a bacillus, ...